Selected publications

2008

Lonjon N, Prieto M, Haton H, Brochner C, Bauchet L, Costalat V, Privat A, Gaviria M and Perrrin F. Minimum information about animal experiment: supplier is also important. Submitted to Nature Methods. 2008.

Dromard C, Guillon H, Rigau V, Ripoll C, Sabourin JC, Perrin F, Scamps F, Bozza S, Sabatier P, Lonjon N, Duffau H, Vachiery-Lahaye F, Prieto M, Tran Van Ba C, Deleyrolle L, Boularan A, Langley K, Gaviria M, Privat A, Hugnot JP, Bauchet L. Adult human spinal cord harbours neural precursor cells that generate neurons and glial cells in vitro. Journal of Neuroscience Research (in press). 2008.

2007

Vandame D, Desmadryl G, Becerril Ortega J, Teigell M, Crouzin N, Buisson A, Privat A, Hirbec H. Comparison of the pharmacological properties of GK11 and MK801, two NMDA receptor antagonists: towards an explanation for the lack of intrinsic neurotoxicity of GK11. J Neurochem. 2007 Oct 1; (Epub ahead of print). 2007

2006

Gaviria M, Bonny JM, Haton H, Jean B, Teigell M, Renou JP, Privat A. Time course of acute phase in mouse spinal cord injury monitored by ex vivo quantitative MRI. Neurobiol Dis. 2006, 22:694-701. (download pdf)

Fawcett JW, Curt A, Steeves JD, Coleman WP, Tuszynski MH, Lammertse D, Bartlett PF, Blight AR, Dietz V, Ditunno J, Dobkin BH, Havton LA, Ellaway PH, Fehlings MG, Privat A, Grossman R, Guest JD, Kleitman N, Nakamura M, Gaviria M, Short D. Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP panel: spontaneous recovery after spinal cord injury and statistical power needed for therapeutic clinical trials. Spinal Cord. 2006.

Steeves JD, Lammertse D, Curt A, Fawcett JW, Tuszynski MH, Ditunno JF, Ellaway PH, Fehlings MG, Guest JD, Kleitman N, Bartlett PF, Blight AR, Dietz V, Dobkin BH, Grossman R, Short D, Nakamura M, Coleman WP, Gaviria M, Privat A. Guidelines for the conduct of clinical trials for spinal cord injury (SCI) as developed by the ICCP panel: clinical trial outcome measures. Spinal Cord. 2006.

Tuszynski MH, Steeves JD, Fawcett JW, Lammertse D, Kalichman M, Rask C, Curt A, Ditunno JF, Fehlings MG, Guest JD, Ellaway PH, Kleitman N, Bartlett PF, Blight AR, Dietz V, Dobkin BH, Grossman R, Privat A. Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP Panel: clinical trial inclusion/exclusion criteria and ethics. Spinal Cord. 2006.

Lammertse D, Tuszynski MH, Steeves JD, Curt A, Fawcett JW, Rask C, Ditunno JF, Fehlings MG, Guest JD, Ellaway PH, Kleitman N, Blight AR, Dobkin BH, Grossman R, Katoh H, Privat A, Kalichman M. Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP panel: clinical trial design. Spinal Cord. 2006.

Rakotoarivelo C, Petite D, de Weille J, Lumbroso S, Privat A, Sultan C, Mersel M. Mild surfection of neural cells, especially motoneurons, in primary culture and cell lines. Exp Neurol, (in press).

Dromard C, Bartolami S, Deleyrolle L, Takebayashi H, Ripoll C, Simonneau L, Prome S, Puech S, Tran Van Ba C, Duperray C, Valmier J, Privat A, Hugnot JP. NG2 and olig2 expression provides evidence for phenotypic deregulation of cultured CNS and PNS neural precursor cells. Stem Cells, (in press).

2005

Anderson DK, Beattie M, Blesch A, Bresnahan J, Bunge M, Dietrich D, Dietz V, Dobkin B, Fawcett J, Fehlings M, Fischer I, Grossman R, Guest J, Hagg T, Hall ED, Houle J, Kleitman N, McDonald J, Murray M, Privat A, Reier P, Steeves J, Steward O, Tetzlaff W, Tuszynski MH, Waxman SG, Whittemore S, Wolpaw J, Young W, Zheng B. Recommended guidelines for studies of human subjects with spinal cord injury. Spinal Cord. 2005.

Hirbec H, Martin S, Henley JM. Syntenin is involved in the developmental regulation of neuronal membrane architecture. Mol Cell Neurosci. 2005 28:737-46.

Gaviria M, Privat A. Strategies for repair in spinal cord traumatic injury. J Neuroradiol (in press).

2004

Bonny JM, Gaviria M, Donnat JP, Beatrix J, Privat A, Renou JP. Nuclear magnetic resonance micro-imaging of mouse spinal cord in vivo. Neurobiol Dis 2004, 15:474-82 (download pdf)

Cambonie G, Hirbec H, Michaud M, Kamenka JM, Barbanel G. Prenatal infection obliterates the glutamate-related protection against free hydroxyl radicals in neonatal rat brain. J Neurosci Res 2004,75:125-32.

Chauvet N, Privat A, Prieto M. Differential expression of p120 catenin in glial cells of the adult rat brain. J Comp Neurol. 2004 479:15-29.

Mausset-Bonnefont AL, Hirbec H, Bonnefont X, Privat A, Vignon J, de Seze R. Acute exposure to GSM 900-MHz electromagnetic fields induces glial reactivity and biochemical modifications in the rat brain. Neurobiol Dis. 2004 17:445-54.

Rakotoarivelo C, Petite D, Lambard S, Fabre C, Rouleau C, Lumbroso S, de Weille J, Privat A, Carreau S, Mersel M. Receptors to steroid hormones and aromatase are expressed by cultured motoneurons but not by glial cells derived from rat embryo spinal cord. Neuroendocrinology. 2004 80:284-97.

2003

Chauvet N, Prieto M, Fabre C, Noren NK, Privat A.  Distribution of p120 catenin during rat brain development: potential role in regulation of cadherin-mediated adhesion and actin cytoskeleton organization. Mol Cell Neurosci. 2003 22:467-86.

Tadié M, Gaviria M, Mathe JF, et al. Early care and treatment with a neuroprotective drug, Gacyclidine, in patients with acute spinal cord injury. Rachis 2003, 15:363-376.

Chauvet N, Prieto M, Fabre C, Noren N K, Privat A. Distribution of p120 catenin during rat brain development: potential role in regulation of cadherin-mediated adhesion and actin cytoskeleton organization. Mol Cell Neurosci 2003,22:467-86.

Cho K, Francis JC, Hirbec H, Dev K, Brown MW, Henley JM, Bashir ZI. Regulation of kainate receptors by protein kinase C and metabotropic glutamate receptors. J Physiol 2003,548:723-30.

Hirbec H, Francis JC, Lauri SE, Braithwaite SP, Coussen F, Mulle C,. Dev KK, Couthino V, Meyer G, Isaac JTR, Collingridge GL and JM Henley, Rapid and differential regulation of AMPA and kainate receptors at hippocampal mossy fibre synapses by PICK1 and GRIP. Neuron 2003,37:625-38.

Marchal-Victorion S, Deleyrolle L, De Weille J, Saunier M, Dromard C, Sandillon F, Privat A, Hugnot JP. The human NTERA2 neural cell line generates neurons on growth under neural stem cell conditions and exhibits characteristics of radial glial cells. Mol Cell Neurosci 2003,24:198-213.Mausset-Bonnefont AL, de Seze R, Privat A. Immunohistochemistry as a tool for topographical semi-quantification of neurotransmitters in the brain. Brain Res Brain Res Protoc 2003,10:148-55.

Menet V, Prieto M, Privat A, Gimenez y Ribotta M. Axonal plasticity and functional recovery after spinal cord injury in mice deficient in both glial fibrillary acidic protein and vimentin genes. Proc Natl Acad Sci U S A 2003,100:8999-9004.

Privat A. Astrocytes as support for axonal regeneration in the central nervous system of mammals. Glia 2003,43:91-3.

2002

Gaviria M, Haton H, Sandillon F, Privat A. A mouse model of acute ischemic spinal cord injury. J Neurotrauma 2002,19:205-21.

Gimenez y Ribotta M, Gaviria M, Menet V, Privat A. Strategies for regeneration and repair in spinal cord traumatic injury. Prog Brain Res 2002,137:191-212.

Hirbec H, Mausset AL, Kamenka JM, Privat A, Vignon J., Re-evaluation of phencyclidine low-affinity or "non-NMDA" binding sites. J Neurosci Res 2002,68:305-14.

Hirbec H, Perestenko O, Nishimune A, Meyer G, Nakanishi S, Henley JM, Dev KK., The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs. J Biol Chem 2002,277:15221-4.

Orsal D, Barthe JY, Antri M, Feraboli-Lohnherr D, Yakovleff A, Gimenez y Ribotta M, Privat A, Provencher J, Rossignol S. Locomotor recovery in chronic spinal rat: long-term pharmacological treatment or transplantation of embryonic neurons? Prog Brain Res 2002,137:213-30.

2001

Gaviria M, Privat A. Physiopathologie de la lésion médullaire : la lésion secondaire. Rachis 2001,13: 239-46.

Gimenez y Ribotta M, Menet V, Privat A. The role of astrocytes in axonal regeneration in the mammalian CNS. Prog Brain Res 2001,132:587-610.

Hirbec H, Gaviria M, Vignon J., Gacyclidine: a new neuroprotective agent acting at the N-methyl-D-aspartate receptor. CNS Drug Rev 2001,7:172-98.

Hirbec H, Kamenka JM, Privat A, Vignon J., Interaction of gacyclidine enantiomers with 'non-NMDA' binding sites in the rat central nervous system. Brain Res 2001,894:189-92.

Hirbec H, Kamenka JM, Privat A, Vignon J., Characterization of 'non-N-methyl-D-Aspartate' binding sites for gacyclidine enantiomers in the rat cerebellar and telencephalic structures. J Neurochem 2001,77:190-201.

Menet V, Gimenez y Ribotta M, Chauvet N, Drian M J, Lannoy J, Colucci-Guyon E, Privat A. Inactivation of the glial fibrillary acidic protein gene, but not that of vimentin, improves neuronal survival and neurite growth by modifying adhesion molecule expression. J Neurosci 2001,21:6147-58.

2000

Prieto M, Chauvet N, Alonso G. Tanycytes transplanted into the adult rat spinal cord support the regeneration of lesioned axons. Exp Neurol. 2000, 161:27-37.

Dumoulin A, Privat A, Gimenez y Ribotta M. Transplantation of embryonic Raphe cells regulates the modifications of the GABAergic phenotype occurring in the injured spinal cord. Neuroscience 2000,95:173-82.

Espaze F, Hamon J, Hirbec H, Vignon J, Kamenka JM, The low affinity PCP sites in the rat cerebellum not only bind TCP-like but also BTCP-like structures. Eur J Med Chem 2000,35:323-31.

Gaviria M, Privat A, d'Arbigny P, Kamenka J M, Haton H, Ohanna F. Neuroprotective effects of gacyclidine after experimental photochemical spinal cord lesion in adult rats: dose-window and time-window effects. J Neurotrauma 2000,17:19-30.

Gaviria M, Privat A, d’Arbigny P, Kamenka JM, Haton H, Ohanna F. Neuroprotective effects of Gacyclidine after experimental contusive spinal cord injury in adult rats. Brain Res 2000,874:200-9.

Gimenez Y Ribotta M, Langa F, Menet V, Privat A. Comparative anatomy of the cerebellar cortex in mice lacking vimentin, GFAP, and both vimentin and GFAP. Glia 2000,31:69-83.

Giménez y Ribotta M, Provencher J, Feraboli-Lohnherr D, Rossignol S, Privat A, Orsal D. Activation of locomotion in adult chronic spinal rats is achieved by transplantation of embryonic raphe cells reinnervating a precise lumbar level. J Neurosci 2000,20:5144-52.

Guillemain I, Alonso G, Patey G, Privat A, Chaudieu I. Human NT2 neurons express a large variety of neurotransmission phenotypes in vitro. J Comp Neurol 2000,422:380-95.

Hirbec H, Privat A, Vignon J., Binding properties of [3H]gacyclidine in the rat central nervous system. Eur J Pharmacol 2000,388:235-9.

Hirbec H, Teilhac J, Kamenka J, Privat A, Vignon J., Binding properties of [3H]gacyclidine (cis(pip/me)-1-[1-(2-thienyl)-2 methylcyclohexyl]piperidine) enantiomers in the rat central nervous system. Brain Res 2000,859:177-92.

Menet V, Gimenez Y Ribotta M, Sandillon F, Privat A. GFAP null astrocytes are a favorable substrate for neuronal survival and neurite growth. Glia 2000,31:267-72.

Privat A, Gaviria M, Gimenez y Ribotta M. Neuroprotection and regeneration in spinal cord injury. Eur Neuropsychopharmacol 2000,10 S3:154-5.

Privat A, Gimenez y Ribotta M, Orsal D. What is a functional recovery after spinal cord injury? Nat Med 2000,6:358.

Ridet JL, Pencalet P, Belcram M, Giraudeau B, Chastang C, Philippon J, Mallet J, Privat A, Schwartz L. Effects of spinal cord X-irradiation on the recovery of paraplegic rats. Exp Neurol 2000,161:1-14.

Ridet I, Privat A. Volume transmission. Trends Neurosci 2000,23:58-9.

1990 – 1999

Alonso G, Prieto M, Chauvet N. Tangential migration of young neurons arising from the subventricular zone of adult rats is impaired by surgical lesions passing through their natural migratory pathway. J Comp Neurol. 1999, 405:508-28

Audouy S, Mallet J, Privat A, Gimenez y Ribotta M. Adenovirus-mediated suicide gene therapy in an in vitro model of reactive gliosis. Glia 1999, 25:293-303.

Chaudieu I, Privat A. Neuroprotection of cultured foetal rat hippocampal cells against glucose deprivation: are GABAergic neurons less vulnerable or more sensitive to TCP protection? Eur J Neurosci 1999, 11:2413-21.

Drian MJ, Kamenka JM, Privat A. In vitro neuroprotection against glutamate toxicity provided by novel non-competitive N-methyl-D-aspartate antagonists. J Neurosci Res 1999,57:927-34.

Gaviria M, Ohanna F. Variability of the fatigue response of the paralyzed skeletal muscle related to the delay of spinal cord injury: mechanical and electrophysiological characteristics. Eur J Appl Physiol Occup Physiol 1999, 80:145-53.

Giménez y Ribotta M, Privat A. Biological interventions for spinal cord injury. Curr Opin Neurol 1998,11:647-54.

Chauvet N, Prieto M, Alonso G. Tanycytes present in the adult rat mediobasal hypothalamus support the regeneration of monoaminergic axons. Exp Neurol. 1998 151:1-13.

Alonso G, Prieto M, Legrand A, Chauvet N. PSA-NCAM and B-50/GAP-43 are coexpressed by specific neuronal systems of the adult rat mediobasal hypothalamus that exhibit remarkable capacities for morphological plasticity. J Comp Neurol. 1997, 384:181-99.

Feraboli-Lohnherr D, Orsal D, Yakovleff A, Gimenez y Ribotta M, Privat A. Recovery of locomotor activity in the adult chronic spinal rat after sublesional transplantation of embryonic nervous cells: specific role of serotonergic neurons. Exp Brain Res 1997,113:443-54.Alonso G, Prieto M, Chauvet N. Tangential migration of young neurons arising from the subventricular zone of adult rats is impaired by surgical lesions passing through their natural migratory pathway. J Comp Neurol. 1999, 405:508-28

Audouy S, Mallet J, Privat A, Gimenez y Ribotta M. Adenovirus-mediated suicide gene therapy in an in vitro model of reactive gliosis. Glia 1999, 25:293-303.

Chaudieu I, Privat A. Neuroprotection of cultured foetal rat hippocampal cells against glucose deprivation: are GABAergic neurons less vulnerable or more sensitive to TCP protection? Eur J Neurosci 1999, 11:2413-21.

Drian MJ, Kamenka JM, Privat A. In vitro neuroprotection against glutamate toxicity provided by novel non-competitive N-methyl-D-aspartate antagonists. J Neurosci Res 1999,57:927-34.

Gaviria M, Ohanna F. Variability of the fatigue response of the paralyzed skeletal muscle related to the delay of spinal cord injury: mechanical and electrophysiological characteristics. Eur J Appl Physiol Occup Physiol 1999, 80:145-53.

Giménez y Ribotta M, Privat A. Biological interventions for spinal cord injury. Curr Opin Neurol 1998,11:647-54.

Chauvet N, Prieto M, Alonso G. Tanycytes present in the adult rat mediobasal hypothalamus support the regeneration of monoaminergic axons. Exp Neurol. 1998 151:1-13.

Alonso G, Prieto M, Legrand A, Chauvet N. PSA-NCAM and B-50/GAP-43 are coexpressed by specific neuronal systems of the adult rat mediobasal hypothalamus that exhibit remarkable capacities for morphological plasticity. J Comp Neurol. 1997, 384:181-99.

Feraboli-Lohnherr D, Orsal D, Yakovleff A, Gimenez y Ribotta M, Privat A. Recovery of locomotor activity in the adult chronic spinal rat after sublesional transplantation of embryonic nervous cells: specific role of serotonergic neurons. Exp Brain Res 1997,113:443-54.

Chammas M, Rabischong E, Picot MC, Gaviria M, Roger P, Micallef JP, Préfaut C, Allieu Y. Functional and histological effects of a free non vascularized muscle graft implanted into a late reinnervated muscle after prolonged denervation. Microsurgery 1997,17:545-50.

Ridet JL, Malhotra SK, Privat A, Gage FH. Reactive astrocytes: cellular and molecular cues to biological function. Trends Neurosci 1997,20:570-7.

Galou M, Colucci-Guyon E, Ensergueix D, Ridet JL, Gimenez y Ribotta M, Privat A, Babinet C, Dupouey P. Disrupted glial fibrillary acidic protein network in astrocytes from vimentin knockout mice. J Cell Biol 1996,133:853-63.

Yakovleff A, Cabelguen J M, Orsal D, Gimenez y Ribotta M, Rajaofetra N, Drian MJ, Bussel B, Privat A. Fictive motor activities in adult chronic spinal rats transplanted with embryonic brainstem neurons. Exp Brain Res 1995,106:69-78.

Ridet JL, Rajaofetra N, Teilhac JR, Geffard M, Privat A. Evidence for nonsynaptic serotonergic and noradrenergic innervation of the rat dorsal horn and possible involvement of neuron-glia interactions. Neuroscience 1993,52:143-57.

Pencalet P, Ohanna F, Poulat P, Kamenka JM, Privat A. Thienylphencyclidine protection for the spinal cord of adult rats against extension of lesions secondary to a photochemical injury. J Neurosurg 1993,78:603-9.

Levallois C, Calvet MC, Kamenka JM, Petite D, Privat A. TCP enhances the survival of human fetal spinal cord cells in culture. Brain Res 1992,573:327-30.

Rajaofetra N, Konig N, Poulat P, Marlier L, Sandillon F, Drian MJ, Geffard M, Privat A. Fate of B1-B2 and B3 rhombencephalic cells transplanted into the transected spinal cord of adult rats: light and electron microscopic studies. Exp Neurol 1992,117:59-70.

Rajaofetra N, Poulat P, Marlier L, Sandillon F, Drian MJ, Konig N, Famose F, Verschuere B, Gouy D, Geffard M, Privat A. Transplantation of embryonic serotonin immunoreactive neurons into the transected spinal cord of adult monkey (Macaca fascicularis). Brain Res 1992,572:329-34.

1970– 1989

Privat A, Mansour H, Geffard M. Transplantation of fetal serotonin neurons into the transected spinal cord of adult rats: morphological development and functional influence. Prog Brain Res 1988,78:155-66.

Gueneau G, Privat A, Drouet J, Court L. Subgranular zone of the dentate gyrus of young rabbits as a secondary matrix. A high-resolution autoradiographic study. Dev Neurosci 1982,5:345-58.

Privat A, Valat J, Fulcrand J. Proliferation of neuroglial cell lines in the degenerating optic nerve of young rats. A radioautographic study. J Neuropathol Exp Neurol 1981,40:46-60.

Privat A, Jacque C, Bourre JM, Dupouey P, Baumann N. Absence of the major dense line in myelin of the mutant mouse "shiverer". Neurosci Lett 1979,12:107-12.

Fulcrand J, Privat A. Neuroglial reactions secondary to Wallerian degeneration in the optic nerve of the postnatal rat: ultrastructural and quantitative study. J Comp Neurol 1977,176:189-222.

Privat A. Postnatal gliogenesis in the mammalian brain. Int Rev Cytol 1975,40:281-323.

Paterson JA, Privat A, Ling EA, Leblond CP. Investigation of glial cells in semithin sections. 3. Transformation of subependymal cells into glial cells, as shown by radioautography after 3 H-thymidine injection into the lateral ventricle of the brain of young rats. J Comp Neurol 1973,149:83-102.

Privat A, Leblond CP. The subependymal layer and neighboring region in the brain of the young rat. J Comp Neurol 1972,146:277-302.

Privat A, Robain O, Mandel P. Ultrastructural study of the corpus callosum in Jimpy mice. Acta Neuropathol (Berl) 1972,21:282-95.